Harpreet Wasan.

Disease and Survival Progression The final analysis was event-powered and performed 8 months after the last patient was signed up for the trial, of which point 327 deaths had occurred , including 10 noncancer deaths and 37 deaths that the cause was unknown. A total of 362 patients had tumor progression , of whom 278 died. Figure 2AFigure 2Outcomes in Patients with Biliary Tract Cancers Who Received Gemcitabine Alone versus Cisplatin plus Gemcitabine.7 months , as compared with 8.1 months for the gemcitabine-only group . Sufferers who received cisplatin plus gemcitabine were 36 percent less likely to die anytime than those that received gemcitabine alone . Adjustment for the randomization stratification factors did not significantly alter this result .The report is on-line.

Camille E. Powe, M.D., Michele K. Evans, M.D., Julia Wenger, M.P.H., Alan B. Zonderman, Ph.D., Anders H. Berg, M.D., Ph.D., Michael Nalls, Ph.D., Hector Tamez, M.D., M.P.H., Dongsheng Zhang, Ph.D., Ishir Bhan, M.D., M.P.H., S. Ananth Karumanchi, M.D., Neil R. Powe, M.D., M.P.H., M.B.A., and Ravi Thadhani, M.D., M.P.H. 1-4 Such research are responsible for the routine medical practice of screening for supplement D insufficiency. Among the possible effects of vitamin D insufficiency, the strongest evidence is for a role in skeletal disorders,5,6 but clinical investigations of supplement D supplementation to decrease the chance of fracture have been inconclusive.7-10 Because blacks consistently have lower levels of total 25-hydroxyvitamin D than whites, they are frequently given a medical diagnosis of vitamin D insufficiency.11-13 Yet, as compared with whites, blacks possess higher bone mineral density and a lesser threat of fragility fracture.14-16 Elevated degrees of parathyroid hormone, considered a sensitive marker of vitamin D deficiency often, are more common in blacks than in whites.