According to Dr. Jean-Claude Tardif a Universit – de Montr-al Montreal and professor Center Institute researcher, the physiological response to stress in women and older men is associated with this desire of preserving self-esteem and securing cultural bonds. ‘The sense of belonging is usually a basic human want,’ says D’Antono. ‘Our results suggest that socialization can be innate and that belonging to a group contributed to the survival of our ancestors. Today, it is possible that most people view sociable exclusion as a danger to their existence. A strong defensive reaction pays to to keep up one’s self-esteem faced with this potential risk.’ As part of the experiment, individuals completed four tasks of varying stress amounts.The handles did not have a brief history of leprosy, autoimmune, or systemic disorders or a grouped genealogy of leprosy . Controls and Patients self-reported their age, sex, and ethnic group on a questionnaire. All individuals reported that these were free of an infection by M. Tuberculosis and chronic an infection by other agents . Controls and Individuals were matched according to ethnic origin and geographic area of recruitment. All individuals provided written educated consent, and the analysis was approved by regional institutional ethics committees . We carried out the genomewide association research using Human610-Quad BeadChip and the follow-up genotyping using the iPLEX program and the TaqMan assay .